[ET]
The cause of cervical leukoplakia not yet clear, and may be related to the following factors:
(A) of endocrine disorders: in estrogen levels increase, resulting in abnormal cervical epithelial surface keratosis.
(B) stimulate the local: such as chronic inflammation of cervical, vaginal trichomoniasis and the impact. Zhongshan Medical University in 700 cases of cervical erosion biopsy clinical pathology analysis, we found 37 cases of cervical leukoplakia, or 5.2 percent, in the foreseeable Man Xingzi cervicitis cases, the rate increased significantly.
(C) other factors: According to literature, even with the white spot cervical dysplasia, carcinoma in situ or invasive early coexist. That the incidence of cervical leukoplakia, may cause cancer and cervical cancer-related factors.
[Pathological changes:
In general observation, that cervical surface opaque white spot Flake region, size, shape different, generally smaller lesions, the diameter of not more than 1 cm. Single or more, individual cases of leukoplakia can go beyond the cervix of vaginal fornix. To the surface than the surrounding off-white or only slightly shiny pink mucosa, the edge of some neat, clear boundaries, while others are Bu Zhengqi, with Cotton will be easy to wipe the surface of white spots, the point at the bottom was bleeding.
Endoscopic findings have the following characteristics: ① leukoplakia the surface excessive keratosis or incomplete keratosis; ② epithelial cell proliferation, mast, with spine cell layer thickness; ③ granule cell layer thickness, epithelial legs extended, widened; ④ on the cortex of mesenchymal cells are round and lymphocyte infiltration. It was based on morphological characteristics of organizations, will be divided into two cervical leukoplakia, cervical epithelial surface layer only 2 to 3 keratosis or incomplete keratosis, the spine under the basal cell layer cells and maintain a normal or benign, as leukoplakia Ⅰ level; keratosis of the epithelial cells of atypical hyperplasia, as leukoplakia Ⅱ.
The cause of cervical leukoplakia not yet clear, and may be related to the following factors:
(A) of endocrine disorders: in estrogen levels increase, resulting in abnormal cervical epithelial surface keratosis.
(B) stimulate the local: such as chronic inflammation of cervical, vaginal trichomoniasis and the impact. Zhongshan Medical University in 700 cases of cervical erosion biopsy clinical pathology analysis, we found 37 cases of cervical leukoplakia, or 5.2 percent, in the foreseeable Man Xingzi cervicitis cases, the rate increased significantly.
(C) other factors: According to literature, even with the white spot cervical dysplasia, carcinoma in situ or invasive early coexist. That the incidence of cervical leukoplakia, may cause cancer and cervical cancer-related factors.
[Pathological changes:
In general observation, that cervical surface opaque white spot Flake region, size, shape different, generally smaller lesions, the diameter of not more than 1 cm. Single or more, individual cases of leukoplakia can go beyond the cervix of vaginal fornix. To the surface than the surrounding off-white or only slightly shiny pink mucosa, the edge of some neat, clear boundaries, while others are Bu Zhengqi, with Cotton will be easy to wipe the surface of white spots, the point at the bottom was bleeding.
Endoscopic findings have the following characteristics: ① leukoplakia the surface excessive keratosis or incomplete keratosis; ② epithelial cell proliferation, mast, with spine cell layer thickness; ③ granule cell layer thickness, epithelial legs extended, widened; ④ on the cortex of mesenchymal cells are round and lymphocyte infiltration. It was based on morphological characteristics of organizations, will be divided into two cervical leukoplakia, cervical epithelial surface layer only 2 to 3 keratosis or incomplete keratosis, the spine under the basal cell layer cells and maintain a normal or benign, as leukoplakia Ⅰ level; keratosis of the epithelial cells of atypical hyperplasia, as leukoplakia Ⅱ.
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