Cervical polyps from cervical epithelial and stromal hyperplasia formation of limitations had polyps bar. Most cervical polyps are inflammatory polyps, that is, symptoms of inflammation due to stimulation from endometrial hyperplasia, or there may be a minority for the gland polyps but in the pathological examination, we will be called cervical adenoid proliferation and has not been done Cervical adenomatous polyposis diagnosis. This paper will be in October 1986 to October 2005, 190 cases analyzed as follows:
1 Materials and Methods
1.1 of our hospital from October 1986 to October 2005 for the clinical diagnosis of cervical polyps in patients with a retrospective analysis
1.2 original specimens are used conventional fixed, sliced and stained.
1.3 pairs of the cases were followed up for cervical smears, relapse again removed, to do with the seizure of morphological contrast to the original biopsy.
1.4 age group of under 30 years of age and above all for the 61-year-old age group, aged 31 to 60 years each for a group of 5-year-old.
2 observation
2.1 parts from the 156 cases of cervical vaginal Ministry of 18 cases of cervical, uterine 13 cases, three cases of malignant.
2.2 age distribution
Age recorded 183 cases, 30 were under the age of 13 cases, accounting for 7.1 percent; 31 to 35-year-old in 17 cases, accounting for 9.3 percent of 36 to 40-year-old 29 cases, accounting for 15.8 percent; 41 to 45 years in 41 cases, accounting for 22.4% ; 46 to 50-year-old 35 cases, accounting for 19.1 percent; 51 to 55-year-old 30 cases, accounting for 16.4 percent; 56 to 60-year-old in 11 cases, accounting for 6.0%; 6 l over the age of seven cases, accounting for 3.8 percent; no records were seven cases of age . Total 190 cases.
3 general observation
Regardless of what comes from the Department, not the size, and so on. Small, a few millimetres, the larger a few centimetres. A round, flat round, the fronds, it may seem small chicken coronavirus or sesame granular. Pink or Huihuang Se. Multi-surface covered in mucus. Beattie length of the source can not, such as different positions. Section is of a size or the Nangqiang. Malignant fragile organizations to adenocarcinoma of the case.
4 microscopy
4.1 of cervical polyps
Single-layer surface was covered columnar epithelium, or the formation of papillary fronds, interstitial edema or part of dense connective tissue. Vascular glands, ranging from the number of inflammatory cells. According to blood vessels, glands, chemical and biological as well as the number of inflammatory cells can be divided into ① gland or adenomatous polyps: single-layer coating the surface columnar epithelium, mesenchymal to the neck glands-based, small blood vessels, glands Adenomatous hyperplasia and form the structure. Interstitial edema, infiltration of inflammatory cells Waterloo, ranging from the number of metaplasia. ② vascular, single-storey cylindrical surface of epithelial, stromal below for a high degree of congestive large size of the vessel. Glands of the neck of little or no. Mesenchymal loose with infiltration of inflammatory cells. ③ granulomatous inflammation: the surface epithelium or disappearance of some disappeared, surface and deep for the large number of inflammatory cells and new small blood vessels, organizational structure like inflammatory granulation tissue. ④ of nature: its quality is nested between the squamous metaplasia epithelial cells of the spine may even have a cavity or keratosis, cell nest and the nest was squeezed between the connective tissue, a small amount of inflammatory cell infiltration. ⑤ fiber: single-layer coating the surface columnar epithelium, for mesenchymal loose fibers, no glands, that some very small amount of blood vessels. ⑥ mixed: from cervical isthmus at the junction of cervix, for the single-storey cylindrical surface of epithelial, stromal a neck glands and the type of endometrial glands.
4.2 polyps surface of the cervix and vagina for the rehabilitation of the squamous cell. The bottom part of the connective tissue edema, or dense fibrous tissue, neck glands gland cavity of the type or size branch-like, or for mesenchymal loose fibers, glands absent.
4.3 uterine polyps that Beattie has been a long fall to the cervix I, for the single-storey cylindrical surface of epithelial, stromal and endometrial glands to-surface ranging from the number of infiltration of inflammatory cells.
Uterine fibroids are based gland often fall into the vagina of the cervix, a round or oval-shaped, large, few centimeters, of hard, solid section, or a small Nangqiang. Under for the smooth muscle fibers are intertwined, a small amount of endometrial glands. Surface often infection, was Adenomyoma. (This article is not included in the statistics).
4.4 malignant polyp
Complex layers are extremely squamous cell disorder, nuclear chromatin depth, size. According to the extent malignant cancer and cervical carcinoma in situ or similar organizations image. Gland malignant organizations fragile, glandular epithelium lining narrow cavity was false-layer, or papilloma. Deep into the nuclear chromatin or loose particles, mesenchymal less, and adenocarcinoma similar images.
5 discussion
Clinical symptoms of cervical polyps of different, sometimes without any symptoms, from the census found gynecology. Also through contact with bleeding, Leucorrhea increased symptoms such as back pain treatment. Organization and the location of different forms, clinical manifestations are also different.
5.1 of cervical polyps
Most people think that because of chronic inflammation caused hyperplasia prominent cervical mouth, the most common type of this information 80.20 percent. I highlight because of neck contact with the outside world, serious surface fester inflammatory granulation tissue formation. Clinical symptoms of chronic cervicitis. Vascular vessel to its roots Shenru mesenchymal, branch-like growth. As Beattie long been squeezed, stromal vascular back rent, a high degree of vascular congestion, wall thinning, clinical manifestations contact hemorrhage, or bleeding with intravenous drip after it, such as bloody Leucorrhea. Adenomatous relatively rare type of information in this paper 4.20 percent. Films such as uterine biopsy meat cases diagnosed adenomatous hyperplasia, often regarded as precancerous lesions. Adenomatous polyps hyperplasia, should be further checks to prevent cervical or Palace of malignant lesions coexist.
Polyp metaplasia more common. This naturally refers to cultural organizations in whole or in the vast majority of polyps for squamous cell metaplasia. The 30-year-old information below, chemical and biological fertility rate higher, accounting for 51.6 percent of this age group. Other age group accounted for about 18%. Metaplasia in this age group is high, may be of child-bearing age to stimulate the local resistance to enhance the performance of the positive role of functional adaptation. Polyp from the observation of chemical and biological organizations, is also on the skin cell proliferation reserves, columnar epithelium and the epithelial tissue from the final columnar epithelium shedding necrosis. Proliferation of cells deep reserves, the Centre keratosis, or the formation of vacuoles, and should be differentiated squamous cell carcinoma of keratosis. Metaplasia in this group of patients with follow-up of 17 people, six were in relapse, accounting for 35 percent of follow-up. No recurrence of symptoms. All 17 were for cervical smear cytology, respectively diagnosis: Ⅰ Ⅱ a class or grade. Relapsed again removed and the original biopsy for comparison, two similar, with no malignant. Reserves increased levels of cell proliferation with disorder, nuclear size, color depth different. This shows that as nuclear fission, was not atypical hyperplasia. Cell proliferation, chemical and biological reserves become mature squamous cell, can long remain unchanged. Such as dysplasia may be cancerous.
5.2 cervix and vagina of the polyp
Its surface-to-squamous cell, mesenchymal gland formed satisfied that the majority's cyst, which may cause the formation of polyps and inflammatory satisfied that the capsule prolapse or laceration after repair due to proliferation. Clinical symptoms of chronic cervicitis.
5.3 uterine polyps often of amenorrhea or irregular bleeding
Endometrial biopsy Changcheng proliferative changes, such polyps more from endometrial basal layer, is not sensitive to the menstrual cycle, so polyps glands Changcheng with the proliferation of adenoid cystic hyperplasia.
5.4 malignant, malignant three cases in this group, aged between 50 to 60-year-old.
Squamous cell malignant two cases, one case of malignant gland, squamous cell, only one case of malignant, bleeding after menopause. The three cases of clinical examination, cervical smooth, a polyp removed. The seizure of malignant polyps. Then do cervical smear, of which two cases cytological diagnosis Ⅴ level, for cervical carcinoma in situ involved gland biopsy, another one case of cytology grade Ⅲ biopsy chronic cervicitis; one case of malignant glands of a small number of irregular bleeding. Removal of polyps found: the malignant gland, uterine biopsy from the Palace of adenocarcinoma. This shows that cervical polyps and malignant cervical or Palace of malignant coexist.
The good of the age, the majority of scholars is different, Chen Zhonghe, [1], and so that 40 to 60-year-old common. In this paper, 190 cases of age in 183 cases recorded, the vast majority of the married mothers, for the good of the age between 36 to 55-year-old. According to text of the records, China's women's average age was 49.5 years old menopause. 39 to 95 percent in the 56-year-old, who menopause before the age of 39 accounted for 4.25 percent. Statistical analysis from this group, the incidence of cervical polyps before the age of 36 after 55 years significantly reduced, with the exception of inflammation, and whether or not related to endocrine changes will be needed to seriously explore.
1 Materials and Methods
1.1 of our hospital from October 1986 to October 2005 for the clinical diagnosis of cervical polyps in patients with a retrospective analysis
1.2 original specimens are used conventional fixed, sliced and stained.
1.3 pairs of the cases were followed up for cervical smears, relapse again removed, to do with the seizure of morphological contrast to the original biopsy.
1.4 age group of under 30 years of age and above all for the 61-year-old age group, aged 31 to 60 years each for a group of 5-year-old.
2 observation
2.1 parts from the 156 cases of cervical vaginal Ministry of 18 cases of cervical, uterine 13 cases, three cases of malignant.
2.2 age distribution
Age recorded 183 cases, 30 were under the age of 13 cases, accounting for 7.1 percent; 31 to 35-year-old in 17 cases, accounting for 9.3 percent of 36 to 40-year-old 29 cases, accounting for 15.8 percent; 41 to 45 years in 41 cases, accounting for 22.4% ; 46 to 50-year-old 35 cases, accounting for 19.1 percent; 51 to 55-year-old 30 cases, accounting for 16.4 percent; 56 to 60-year-old in 11 cases, accounting for 6.0%; 6 l over the age of seven cases, accounting for 3.8 percent; no records were seven cases of age . Total 190 cases.
3 general observation
Regardless of what comes from the Department, not the size, and so on. Small, a few millimetres, the larger a few centimetres. A round, flat round, the fronds, it may seem small chicken coronavirus or sesame granular. Pink or Huihuang Se. Multi-surface covered in mucus. Beattie length of the source can not, such as different positions. Section is of a size or the Nangqiang. Malignant fragile organizations to adenocarcinoma of the case.
4 microscopy
4.1 of cervical polyps
Single-layer surface was covered columnar epithelium, or the formation of papillary fronds, interstitial edema or part of dense connective tissue. Vascular glands, ranging from the number of inflammatory cells. According to blood vessels, glands, chemical and biological as well as the number of inflammatory cells can be divided into ① gland or adenomatous polyps: single-layer coating the surface columnar epithelium, mesenchymal to the neck glands-based, small blood vessels, glands Adenomatous hyperplasia and form the structure. Interstitial edema, infiltration of inflammatory cells Waterloo, ranging from the number of metaplasia. ② vascular, single-storey cylindrical surface of epithelial, stromal below for a high degree of congestive large size of the vessel. Glands of the neck of little or no. Mesenchymal loose with infiltration of inflammatory cells. ③ granulomatous inflammation: the surface epithelium or disappearance of some disappeared, surface and deep for the large number of inflammatory cells and new small blood vessels, organizational structure like inflammatory granulation tissue. ④ of nature: its quality is nested between the squamous metaplasia epithelial cells of the spine may even have a cavity or keratosis, cell nest and the nest was squeezed between the connective tissue, a small amount of inflammatory cell infiltration. ⑤ fiber: single-layer coating the surface columnar epithelium, for mesenchymal loose fibers, no glands, that some very small amount of blood vessels. ⑥ mixed: from cervical isthmus at the junction of cervix, for the single-storey cylindrical surface of epithelial, stromal a neck glands and the type of endometrial glands.
4.2 polyps surface of the cervix and vagina for the rehabilitation of the squamous cell. The bottom part of the connective tissue edema, or dense fibrous tissue, neck glands gland cavity of the type or size branch-like, or for mesenchymal loose fibers, glands absent.
4.3 uterine polyps that Beattie has been a long fall to the cervix I, for the single-storey cylindrical surface of epithelial, stromal and endometrial glands to-surface ranging from the number of infiltration of inflammatory cells.
Uterine fibroids are based gland often fall into the vagina of the cervix, a round or oval-shaped, large, few centimeters, of hard, solid section, or a small Nangqiang. Under for the smooth muscle fibers are intertwined, a small amount of endometrial glands. Surface often infection, was Adenomyoma. (This article is not included in the statistics).
4.4 malignant polyp
Complex layers are extremely squamous cell disorder, nuclear chromatin depth, size. According to the extent malignant cancer and cervical carcinoma in situ or similar organizations image. Gland malignant organizations fragile, glandular epithelium lining narrow cavity was false-layer, or papilloma. Deep into the nuclear chromatin or loose particles, mesenchymal less, and adenocarcinoma similar images.
5 discussion
Clinical symptoms of cervical polyps of different, sometimes without any symptoms, from the census found gynecology. Also through contact with bleeding, Leucorrhea increased symptoms such as back pain treatment. Organization and the location of different forms, clinical manifestations are also different.
5.1 of cervical polyps
Most people think that because of chronic inflammation caused hyperplasia prominent cervical mouth, the most common type of this information 80.20 percent. I highlight because of neck contact with the outside world, serious surface fester inflammatory granulation tissue formation. Clinical symptoms of chronic cervicitis. Vascular vessel to its roots Shenru mesenchymal, branch-like growth. As Beattie long been squeezed, stromal vascular back rent, a high degree of vascular congestion, wall thinning, clinical manifestations contact hemorrhage, or bleeding with intravenous drip after it, such as bloody Leucorrhea. Adenomatous relatively rare type of information in this paper 4.20 percent. Films such as uterine biopsy meat cases diagnosed adenomatous hyperplasia, often regarded as precancerous lesions. Adenomatous polyps hyperplasia, should be further checks to prevent cervical or Palace of malignant lesions coexist.
Polyp metaplasia more common. This naturally refers to cultural organizations in whole or in the vast majority of polyps for squamous cell metaplasia. The 30-year-old information below, chemical and biological fertility rate higher, accounting for 51.6 percent of this age group. Other age group accounted for about 18%. Metaplasia in this age group is high, may be of child-bearing age to stimulate the local resistance to enhance the performance of the positive role of functional adaptation. Polyp from the observation of chemical and biological organizations, is also on the skin cell proliferation reserves, columnar epithelium and the epithelial tissue from the final columnar epithelium shedding necrosis. Proliferation of cells deep reserves, the Centre keratosis, or the formation of vacuoles, and should be differentiated squamous cell carcinoma of keratosis. Metaplasia in this group of patients with follow-up of 17 people, six were in relapse, accounting for 35 percent of follow-up. No recurrence of symptoms. All 17 were for cervical smear cytology, respectively diagnosis: Ⅰ Ⅱ a class or grade. Relapsed again removed and the original biopsy for comparison, two similar, with no malignant. Reserves increased levels of cell proliferation with disorder, nuclear size, color depth different. This shows that as nuclear fission, was not atypical hyperplasia. Cell proliferation, chemical and biological reserves become mature squamous cell, can long remain unchanged. Such as dysplasia may be cancerous.
5.2 cervix and vagina of the polyp
Its surface-to-squamous cell, mesenchymal gland formed satisfied that the majority's cyst, which may cause the formation of polyps and inflammatory satisfied that the capsule prolapse or laceration after repair due to proliferation. Clinical symptoms of chronic cervicitis.
5.3 uterine polyps often of amenorrhea or irregular bleeding
Endometrial biopsy Changcheng proliferative changes, such polyps more from endometrial basal layer, is not sensitive to the menstrual cycle, so polyps glands Changcheng with the proliferation of adenoid cystic hyperplasia.
5.4 malignant, malignant three cases in this group, aged between 50 to 60-year-old.
Squamous cell malignant two cases, one case of malignant gland, squamous cell, only one case of malignant, bleeding after menopause. The three cases of clinical examination, cervical smooth, a polyp removed. The seizure of malignant polyps. Then do cervical smear, of which two cases cytological diagnosis Ⅴ level, for cervical carcinoma in situ involved gland biopsy, another one case of cytology grade Ⅲ biopsy chronic cervicitis; one case of malignant glands of a small number of irregular bleeding. Removal of polyps found: the malignant gland, uterine biopsy from the Palace of adenocarcinoma. This shows that cervical polyps and malignant cervical or Palace of malignant coexist.
The good of the age, the majority of scholars is different, Chen Zhonghe, [1], and so that 40 to 60-year-old common. In this paper, 190 cases of age in 183 cases recorded, the vast majority of the married mothers, for the good of the age between 36 to 55-year-old. According to text of the records, China's women's average age was 49.5 years old menopause. 39 to 95 percent in the 56-year-old, who menopause before the age of 39 accounted for 4.25 percent. Statistical analysis from this group, the incidence of cervical polyps before the age of 36 after 55 years significantly reduced, with the exception of inflammation, and whether or not related to endocrine changes will be needed to seriously explore.
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