Embolization for treatment intervention is the most commonly used methods of treatment, mainly for local bleeding, tumors and vascular malformations of the treatment. Long-term effective treatment of thrombosis, you must use a complete, permanent embolism. When the lesions around the existence of important organizations when asked to be normal artery embolization is a highly selective, to ensure that no damage normal tissue surrounding the lesion.
Research in recent years that the uterus can produce a variety of bioactive substances, and endocrine function, reproductive participation in the body, physiological and pathological processes, pre-menopausal uterus, even with reservations ovary, often caused menopause syndrome, coronary heart disease and osteoporosis The advance of a [1,2]. Therefore, the use of non-surgical treatment of uterine fibroids more and arouse people's attention. But drug treatment will inevitably reduce the level of estrogen the body, affect the normal women's physical and psychological. In recent years, uterine fibroid embolization for the advent of new technologies for the treatment of patients with fibroids opened a new way. Our hospital in August 1998 to July 2000, from 11 patients with gynecological clinic choice based on clinical symptoms, gynaecological check-ups and B-ultrasound or MRI for the diagnosis of patients with uterine fibroids, uterine artery embolization for the treatment line, has been satisfied with the effect of the recent, The following report.
1 information and methods
1.1 general information age 21 to 52 years old, an average of 42.1 years of age. Of which two cases of non-reproductive history. Fibroids single to six cases, fibroids size of 35 mm × 34mm × 31mm ~ 95mm × 72mm × 82mm; many of those five cases, most have four fibroids, the size of 27 mm × 23mm × 28mm ~ 55mm × 54mm × 55mm. Increased menstrual symptoms for eight cases, have varying degrees of anemia, hemoglobin 50 ~ 89 g / L, an average of 70.5 g / L; dysmenorrhea and pelvic pain six cases, one case of a frequency at the same time, three cases of amenorrhea increased.
1.2 treatment of the femoral artery puncture to the right side beyond the uterine artery embolization super-selective. Before uterine artery embolization contrast, the catheter optional 4 F cobra 2 catheter or 2.6 F microscopic catheter. Such as uterine artery near non-existence of the arterial branch of fibroids, as far as possible beyond these catheter branch. Embolization eight cases of gelatin sponge particles with a diameter of 50 ~ 400 μ m, 4 with polyvinyl alcohol (ployvinyl alcohol, PVA) particles, the diameter of 250 ~ 355 μ m. Embolization master degree fibroid tumors in contrast, were completely disappeared so far.
1.3 Clinical Evaluation (1) clinical symptoms of change, or through out-patient follow-up survey respondents way. (2) before and after operation B-measurement of uterine fibroids the size and volume, after 1,2,4,6,12 and 24 B-month review. On a follow-up to 2 years, up more than 3 months have eight cases.
1.4 The results of this power of 100%, 100% efficient obviously, no one case of complications. 10 (90.91%) clinical symptoms completely disappeared, normal menstruation, pelvic pain disappeared one case of pelvic pain in patients with marked improvement, with only mild pain. Three to five days after all patients had varying degrees of upper abdominal discomfort, nausea, abdominal pain or cramps persistent pain, lumbosacral Suanzhang flu, eight cases to be taking painkillers. 10 patients within one week after a vaginal discharges of blood, three cases after the first and second months after amenorrhea, or menstrual irregularities, very little volume, after the first three months since all cases are menstrual Back to normal. Two months later to narrow the scope of fibroid volume in 35.4% ~ 81.0%, an average of 67.2 percent and narrow the range of 60 percent or more in seven cases (7 / 9). One case of a preoperative ultrasound of the four patients with fibroids, including two <3 cm in two months after the B-review can not be detected, considering the sensitivity of B-ultrasound examination limited, B super-under fibroids not found does not mean that all Dissipated, thereby changing the size of the tumor is not included in the survey.
2 discussion
Uterine artery embolization for fibroids was first used in patients with uterine fibroids of fibroids removed, can effectively control bleeding [3]. Later found that some patients with preoperative embolization, the symptoms disappeared, no longer needed surgery. 1996, Los Angeles UCLA Medical Center and Georgetown University Medical Center in Washington with the first uterine artery embolization as a single independent, direct therapy to treat uterine fibroids.
Embolization for treatment intervention is the most commonly used methods of treatment, mainly for local bleeding, tumors and vascular malformations of the treatment. Long-term effective treatment of thrombosis, you must use a complete, permanent embolism. When the lesions around the existence of important organizations when asked to be normal artery embolization is a highly selective, to ensure that no damage normal tissue surrounding the lesion. This focus on certain terms is very difficult, full and complete uterine artery embolization will lead to the uterus and ovarian part of avascular necrosis, which is initially not be treated as a separate embolization treatment applied to the theoretical basis for treating fibroids . But in fact may not be so. Absolutely full use of non-selective, complete with uterine artery embolization on both sides of the uterine fibroid embolization way, embolization, the clinical symptoms of the general improvement of more than 90 percent, moderate to marked improvement in the general account for more than 80 per cent [4] The average size of fibroids reported varying degree of narrowing the higher 70 percent, low of 40% [5,6]. The group significantly improved the clinical symptoms of 100 percent, the clinical symptoms completely disappear accounted for 90.91 percent, the average size of fibroids shrinking 67.2 percent, higher than the general reported in the literature, but fewer cases of this group, and follow-up period long enough, in the long-term effect Pending further observation. We speculate the high effectiveness of this method may be related to fibroids of the high sensitivity of the ischemia, the natural growth of larger fibroids often occur secondary to ischemic degeneration of the fibroids may also note the high sensitivity of ischemia. Fibroid embolization was thus possible effect of the cancer than the general good.
Embolization for a few hours after in-patients often have severe abdominal pain, can cause nausea, vomiting, abdominal pain and other symptoms generally four to seven days later dissipated. Early complication rate reported in the literature <3%, mainly uterine infection and ischemia, a serious need hysterectomy less than one percent. Long-term complications not been reported. In addition to this group, such as pain after the normal reaction after the embolization, no serious side effects and complications. That the author of the highly selective embolization is the prevention of severe ischemia of the normal uterus key part of this group in recent cases of uterine artery of the non-participation of fibroids blood supply, the intubation process of further super-choice, avoid these branches.
Fibroid embolization for the materials, most foreign scholars to use PVA particles, but also a small number of the use of gelatin sponge particles [7]. Consider the price factor, this group use gelatin sponge particles more than PVA. In theory, PVA embolization effective than the gelatin sponge.
Fibroid embolization after the volume was reduced, but the majority of patients with B-review has not been completely dissipated, most of the past reported in the literature is also narrow the size of fibroids, rather than dissipated. Not dissipated long-term effect of how the fibroids, no follow-up results, can not be a conclusion.
In short, the recent effects, the treatment of uterine fibroid embolization is effective, and safe advantages. However, long-term effect, embolization for the treatment of pathological basis, whether the impact on fertility, embolization, such as how to improve the technical aspects to be studied further.
Research in recent years that the uterus can produce a variety of bioactive substances, and endocrine function, reproductive participation in the body, physiological and pathological processes, pre-menopausal uterus, even with reservations ovary, often caused menopause syndrome, coronary heart disease and osteoporosis The advance of a [1,2]. Therefore, the use of non-surgical treatment of uterine fibroids more and arouse people's attention. But drug treatment will inevitably reduce the level of estrogen the body, affect the normal women's physical and psychological. In recent years, uterine fibroid embolization for the advent of new technologies for the treatment of patients with fibroids opened a new way. Our hospital in August 1998 to July 2000, from 11 patients with gynecological clinic choice based on clinical symptoms, gynaecological check-ups and B-ultrasound or MRI for the diagnosis of patients with uterine fibroids, uterine artery embolization for the treatment line, has been satisfied with the effect of the recent, The following report.
1 information and methods
1.1 general information age 21 to 52 years old, an average of 42.1 years of age. Of which two cases of non-reproductive history. Fibroids single to six cases, fibroids size of 35 mm × 34mm × 31mm ~ 95mm × 72mm × 82mm; many of those five cases, most have four fibroids, the size of 27 mm × 23mm × 28mm ~ 55mm × 54mm × 55mm. Increased menstrual symptoms for eight cases, have varying degrees of anemia, hemoglobin 50 ~ 89 g / L, an average of 70.5 g / L; dysmenorrhea and pelvic pain six cases, one case of a frequency at the same time, three cases of amenorrhea increased.
1.2 treatment of the femoral artery puncture to the right side beyond the uterine artery embolization super-selective. Before uterine artery embolization contrast, the catheter optional 4 F cobra 2 catheter or 2.6 F microscopic catheter. Such as uterine artery near non-existence of the arterial branch of fibroids, as far as possible beyond these catheter branch. Embolization eight cases of gelatin sponge particles with a diameter of 50 ~ 400 μ m, 4 with polyvinyl alcohol (ployvinyl alcohol, PVA) particles, the diameter of 250 ~ 355 μ m. Embolization master degree fibroid tumors in contrast, were completely disappeared so far.
1.3 Clinical Evaluation (1) clinical symptoms of change, or through out-patient follow-up survey respondents way. (2) before and after operation B-measurement of uterine fibroids the size and volume, after 1,2,4,6,12 and 24 B-month review. On a follow-up to 2 years, up more than 3 months have eight cases.
1.4 The results of this power of 100%, 100% efficient obviously, no one case of complications. 10 (90.91%) clinical symptoms completely disappeared, normal menstruation, pelvic pain disappeared one case of pelvic pain in patients with marked improvement, with only mild pain. Three to five days after all patients had varying degrees of upper abdominal discomfort, nausea, abdominal pain or cramps persistent pain, lumbosacral Suanzhang flu, eight cases to be taking painkillers. 10 patients within one week after a vaginal discharges of blood, three cases after the first and second months after amenorrhea, or menstrual irregularities, very little volume, after the first three months since all cases are menstrual Back to normal. Two months later to narrow the scope of fibroid volume in 35.4% ~ 81.0%, an average of 67.2 percent and narrow the range of 60 percent or more in seven cases (7 / 9). One case of a preoperative ultrasound of the four patients with fibroids, including two <3 cm in two months after the B-review can not be detected, considering the sensitivity of B-ultrasound examination limited, B super-under fibroids not found does not mean that all Dissipated, thereby changing the size of the tumor is not included in the survey.
2 discussion
Uterine artery embolization for fibroids was first used in patients with uterine fibroids of fibroids removed, can effectively control bleeding [3]. Later found that some patients with preoperative embolization, the symptoms disappeared, no longer needed surgery. 1996, Los Angeles UCLA Medical Center and Georgetown University Medical Center in Washington with the first uterine artery embolization as a single independent, direct therapy to treat uterine fibroids.
Embolization for treatment intervention is the most commonly used methods of treatment, mainly for local bleeding, tumors and vascular malformations of the treatment. Long-term effective treatment of thrombosis, you must use a complete, permanent embolism. When the lesions around the existence of important organizations when asked to be normal artery embolization is a highly selective, to ensure that no damage normal tissue surrounding the lesion. This focus on certain terms is very difficult, full and complete uterine artery embolization will lead to the uterus and ovarian part of avascular necrosis, which is initially not be treated as a separate embolization treatment applied to the theoretical basis for treating fibroids . But in fact may not be so. Absolutely full use of non-selective, complete with uterine artery embolization on both sides of the uterine fibroid embolization way, embolization, the clinical symptoms of the general improvement of more than 90 percent, moderate to marked improvement in the general account for more than 80 per cent [4] The average size of fibroids reported varying degree of narrowing the higher 70 percent, low of 40% [5,6]. The group significantly improved the clinical symptoms of 100 percent, the clinical symptoms completely disappear accounted for 90.91 percent, the average size of fibroids shrinking 67.2 percent, higher than the general reported in the literature, but fewer cases of this group, and follow-up period long enough, in the long-term effect Pending further observation. We speculate the high effectiveness of this method may be related to fibroids of the high sensitivity of the ischemia, the natural growth of larger fibroids often occur secondary to ischemic degeneration of the fibroids may also note the high sensitivity of ischemia. Fibroid embolization was thus possible effect of the cancer than the general good.
Embolization for a few hours after in-patients often have severe abdominal pain, can cause nausea, vomiting, abdominal pain and other symptoms generally four to seven days later dissipated. Early complication rate reported in the literature <3%, mainly uterine infection and ischemia, a serious need hysterectomy less than one percent. Long-term complications not been reported. In addition to this group, such as pain after the normal reaction after the embolization, no serious side effects and complications. That the author of the highly selective embolization is the prevention of severe ischemia of the normal uterus key part of this group in recent cases of uterine artery of the non-participation of fibroids blood supply, the intubation process of further super-choice, avoid these branches.
Fibroid embolization for the materials, most foreign scholars to use PVA particles, but also a small number of the use of gelatin sponge particles [7]. Consider the price factor, this group use gelatin sponge particles more than PVA. In theory, PVA embolization effective than the gelatin sponge.
Fibroid embolization after the volume was reduced, but the majority of patients with B-review has not been completely dissipated, most of the past reported in the literature is also narrow the size of fibroids, rather than dissipated. Not dissipated long-term effect of how the fibroids, no follow-up results, can not be a conclusion.
In short, the recent effects, the treatment of uterine fibroid embolization is effective, and safe advantages. However, long-term effect, embolization for the treatment of pathological basis, whether the impact on fertility, embolization, such as how to improve the technical aspects to be studied further.
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2 comments:
My doctor just called me today to confirm what I was suspecting was happening!! I told my mom and my best friend that I feel like the fibroids are disappearing! I can’t feel them anymore when I press around my lower abdominal area!! Today she confirmed that the scan from last week is showing that they have disappeared! The largest one was about 9cm that one is gone completely!! And that my uterus is almost all the way back to it’s natural size!! I have been praying for healing! At church during healing prayers I will take them by faith. I didn’t change my diet. I’ve just been living upright and obeying the Lord’s commands. Iya hindi root and herbs works with faith and righteous living!!I highly recommend Iya Hindi Native for a solution . To everyone trying to get rid of fibroids.Email: hindinative@yahoo.com , +15302068262 Or,whatsapp messenger: Amen!!!
it's more than a year now since Dr. Uduehi helped shrunk off my long term uterine fibroid. I experienced pelvic pain, heavy menses and swollen. I went to the hospital and was diagnosed of fibroid and advised to go for surgery I hadn’t enough fund on me so I went online for more info and remedy about fibroid. Luckily, I found Dr. Uduehi’s natural medication for fibroid. I reached out to him and the fibroid shrink and disappeared totally after I completed the treatment and is now a year plus since I got cured. His contact: (+234-708-487-8384) (uduehiherbalcare@gmail.com)
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