Oct 17, 2008

Peritoneal mesothelioma

Malignant peritoneal mesothelioma, also known as primary peritoneal mesothelioma, is the origin and peritoneal mesothelium cell tumor of the organization. This rare disease than pleural mesothelioma, slightly higher than the male of female. And the cause of asbestos exposure, the incidence of contact with a long interval, often more than 30 years. Benign mesothelioma often single, located in the fallopian tubes, uterus at the top of the peritoneum, rarely seen in other parts of the body. Malignant mesothelioma is often diffuse, covering all or part of the peritoneum.



【Diagnosis】

1. A history of unexplained abdominal pain question, abdominal distension and gastrointestinal disorders, abdominal pain can be expressed as diversification, but the intractable abdominal pain is a common feature of. The high incidence of ascites in more than 90%, may be in a short period of abdominal pain after the sudden appearance of ascites, ascites, but can also occur in the early alone. Amount of ascites and more stubborn. Body in a fairly long time, very few changes in appetite can be maintained, no weight, no fever, can sometimes occur spontaneously hypoglycemia. Can be accompanied by chest pain, difficulty breathing, coughing, and other symptoms of pleural mesothelioma.



2. Medical examination found that bulging belly or abdomen Frog was, mobility voiced positive; abdominal palpation can reach the size range of single or multiple tumor, the general was not obvious tenderness. As with pleural mesothelioma, pleural effusion can be found positive signs.



3. B laboratory and ultra-CT examination, the thin sheet can be found in tumor images and ascites. For ascites effusion, but also for the courage and uprightness. Ascites, such as hyaluronic acid to increase 120ug/ml, useful for diagnosis. Ascites find new biological value of diagnosis with mesothelioma cells can also be skin cells of ascites in the middle of chromosome analysis, contribute to the diagnosis. Laparoscopic peritoneal found can be seen on the surface covered with plaques and nodules, and biopsy examination can confirm the diagnosis. And the need to pay attention to tuberculous peritonitis, peritoneal metastases with identification.