Jul 20, 2008

Diffuse mesothelioma pathological changes

Early in malignant mesothelioma, visible to the naked eye in the normal or opaque layer of dirt or layer on a large number of pleural white or grey particles and nodules or thin plate, with the development of cancer, pleural thickening the surface more and more, covered with Nodules, tumor extended to the Quartet, for a film, encapsulation lungs to shrink the pits and the smaller side of the chest wall collapse involvement.

Early in malignant mesothelioma, visible to the naked eye in the normal or opaque layer of dirt or layer on a large number of pleural white or grey particles and nodules or thin plate, with the development of cancer, pleural thickening the surface more and more, covered with Nodules, tumor extended to the Quartet, for a film, encapsulation lungs to shrink the pits and the smaller side of the chest wall collapse involvement. Late in the tumor may affect the diaphragm, intercostal muscle, mediastinal structures, and contralateral pleural pericardium. An autopsy found that 50 percent of patients have blood-borne transfer, but of little reference.

There are two malignant mesothelioma autopsy type: ① a single fiber of pleural mesothelioma. From visceral pleural growth, with flat or Roujing, tumor caused the clinical symptoms because they expand the development of chest compression within the structure to shift, if early diagnosis and for treatment. ② wide spread of mesothelioma. This type of lung, diaphragm infiltration, intercostal muscle, which can be involved mediastinal pleura pericardium and great vessels.

The microscope can see malignant mesothelioma have its own characteristics, that is, in a single tumor nodules or the naked eye look the same tumor nodules, have markedly different organizations of various components. Cheung malignant skin tumor pathology credits have E-type, fiber (mesenchymal) and mixed three. E-epithelial cells of a variety of different structures, such as papillary, tubular, the papillary, ribbon work sheet. Polygon epithelial cells have many long, thin, the surface branch of the microvilli, desmosome, a bundle of elastic filaments and cell cavity. Fiber-like spindle-shaped cells, equality configuration, or egg shape slender shape of the nucleus, the nucleolus of good. Mixed with both E-and fiber-two organizational structure. From a block from tumor biopsy, from various parts of the specimens from the more, like the more mixed

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