[Outlined]
Cervical leukoplakia (Leucoplasia of the cervix), means in the cervix of the vagina in a gray opaque Ban Kuaizhuang lesions. Most scholars believe that only white spot of the naked eye can see that there are different degrees of epithelial hyperplasia. As the cervical precancerous lesions and early cancer and colposcopy in-depth study of the extensive application of the disease has been gradually attention.
[Diagnosis]
(A) depending on local consultation: careful observation of cervical local, regional found that white patch, but the naked eye can not identify incomplete keratosis lesions.
(B) Dianye test: keratinized epithelium or incomplete due to lack of keratosis glycogen storage capacity of local non-colored Tu iodine to the scope of diseases can be found. However, iodine test non-specific, such as cervical erosion, valgus or precancerous lesions, such as positive.
(C) colposcopy: Larger colposcopy to observe the cervical lesions, than the eye that is much easier to cervical leukoplakia. Shanghai Second Medical University, has been the subject of colposcopy 1,000 cases and found 79 cases of cervical leukoplakia, accounting for 7.9 percent.
According to local as attending, iodine test and colposcopy, in general it is not difficult to diagnose. But more important is that white spot after further examination, both white spot and avoid missing the early cervical cancer. It was reported in the literature, under the various colposcopy leukoplakia, early cervical cancer is an important performance. For people in 105 cases of carcinoma in situ colposcopy see abnormal changes in the 60 cases, to all types of white spot in the majority (36 cases). White spot on the cervix, should be biopsy to rule out the existence of early cancer.
[Treatment]
As for the white spot benign cervical lesions, the general rule out the possibility of malignant cervical lesions, cervical, for treatment of iron or frozen. Associated with the severe cervical erosion, could be considered Palace cervical-removal, and pathology for biopsy to determine whether early cervical cancer, in order to take timely further treatment. Of asymptomatic patients can be closely observed, regular follow-up.
[ET]
The cause of cervical leukoplakia not yet clear, and may be related to the following factors:
(A) of endocrine disorders: in estrogen levels increase, resulting in abnormal cervical epithelial surface keratosis.
(B) stimulate the local: such as chronic inflammation of cervical, vaginal trichomoniasis and the impact. Zhongshan Medical University in 700 cases of cervical erosion biopsy clinical pathology analysis, we found 37 cases of cervical leukoplakia, or 5.2 percent, in the foreseeable Man Xingzi cervicitis cases, the rate increased significantly.
(C) other factors: According to literature, even with the white spot cervical dysplasia, carcinoma in situ or invasive early coexist. That the incidence of cervical leukoplakia, may cause cancer and cervical cancer-related factors.
[Pathological changes:
In general observation, that cervical surface opaque white spot Flake region, size, shape different, generally smaller lesions, the diameter of not more than 1 cm. Single or more, individual cases of leukoplakia can go beyond the cervix of vaginal fornix. To the surface than the surrounding off-white or only slightly shiny pink mucosa, the edge of some neat, clear boundaries, while others are Bu Zhengqi, with Cotton will be easy to wipe the surface of white spots, the point at the bottom was bleeding.
Endoscopic findings have the following characteristics: ① leukoplakia the surface excessive keratosis or incomplete keratosis; ② epithelial cell proliferation, mast, with spine cell layer thickness; ③ granule cell layer thickness, epithelial legs extended, widened; ④ on the cortex of mesenchymal cells are round and lymphocyte infiltration. It was based on morphological characteristics of organizations, will be divided into two cervical leukoplakia, cervical epithelial surface layer only 2 to 3 keratosis or incomplete keratosis, the spine under the basal cell layer cells and maintain a normal or benign, as leukoplakia Ⅰ level; keratosis of the epithelial cells of atypical hyperplasia, as leukoplakia Ⅱ.
[Clinical]
Leukoplakia more simple cervical asymptomatic, and may naturally dissipated; if the merger cervical erosion or cervical, endometrial valgus, Leucorrhea increase, or sometimes bloody vaginal secretions and contact bleeding. Local checks seen as above.
Cervical leukoplakia (Leucoplasia of the cervix), means in the cervix of the vagina in a gray opaque Ban Kuaizhuang lesions. Most scholars believe that only white spot of the naked eye can see that there are different degrees of epithelial hyperplasia. As the cervical precancerous lesions and early cancer and colposcopy in-depth study of the extensive application of the disease has been gradually attention.
[Diagnosis]
(A) depending on local consultation: careful observation of cervical local, regional found that white patch, but the naked eye can not identify incomplete keratosis lesions.
(B) Dianye test: keratinized epithelium or incomplete due to lack of keratosis glycogen storage capacity of local non-colored Tu iodine to the scope of diseases can be found. However, iodine test non-specific, such as cervical erosion, valgus or precancerous lesions, such as positive.
(C) colposcopy: Larger colposcopy to observe the cervical lesions, than the eye that is much easier to cervical leukoplakia. Shanghai Second Medical University, has been the subject of colposcopy 1,000 cases and found 79 cases of cervical leukoplakia, accounting for 7.9 percent.
According to local as attending, iodine test and colposcopy, in general it is not difficult to diagnose. But more important is that white spot after further examination, both white spot and avoid missing the early cervical cancer. It was reported in the literature, under the various colposcopy leukoplakia, early cervical cancer is an important performance. For people in 105 cases of carcinoma in situ colposcopy see abnormal changes in the 60 cases, to all types of white spot in the majority (36 cases). White spot on the cervix, should be biopsy to rule out the existence of early cancer.
[Treatment]
As for the white spot benign cervical lesions, the general rule out the possibility of malignant cervical lesions, cervical, for treatment of iron or frozen. Associated with the severe cervical erosion, could be considered Palace cervical-removal, and pathology for biopsy to determine whether early cervical cancer, in order to take timely further treatment. Of asymptomatic patients can be closely observed, regular follow-up.
[ET]
The cause of cervical leukoplakia not yet clear, and may be related to the following factors:
(A) of endocrine disorders: in estrogen levels increase, resulting in abnormal cervical epithelial surface keratosis.
(B) stimulate the local: such as chronic inflammation of cervical, vaginal trichomoniasis and the impact. Zhongshan Medical University in 700 cases of cervical erosion biopsy clinical pathology analysis, we found 37 cases of cervical leukoplakia, or 5.2 percent, in the foreseeable Man Xingzi cervicitis cases, the rate increased significantly.
(C) other factors: According to literature, even with the white spot cervical dysplasia, carcinoma in situ or invasive early coexist. That the incidence of cervical leukoplakia, may cause cancer and cervical cancer-related factors.
[Pathological changes:
In general observation, that cervical surface opaque white spot Flake region, size, shape different, generally smaller lesions, the diameter of not more than 1 cm. Single or more, individual cases of leukoplakia can go beyond the cervix of vaginal fornix. To the surface than the surrounding off-white or only slightly shiny pink mucosa, the edge of some neat, clear boundaries, while others are Bu Zhengqi, with Cotton will be easy to wipe the surface of white spots, the point at the bottom was bleeding.
Endoscopic findings have the following characteristics: ① leukoplakia the surface excessive keratosis or incomplete keratosis; ② epithelial cell proliferation, mast, with spine cell layer thickness; ③ granule cell layer thickness, epithelial legs extended, widened; ④ on the cortex of mesenchymal cells are round and lymphocyte infiltration. It was based on morphological characteristics of organizations, will be divided into two cervical leukoplakia, cervical epithelial surface layer only 2 to 3 keratosis or incomplete keratosis, the spine under the basal cell layer cells and maintain a normal or benign, as leukoplakia Ⅰ level; keratosis of the epithelial cells of atypical hyperplasia, as leukoplakia Ⅱ.
[Clinical]
Leukoplakia more simple cervical asymptomatic, and may naturally dissipated; if the merger cervical erosion or cervical, endometrial valgus, Leucorrhea increase, or sometimes bloody vaginal secretions and contact bleeding. Local checks seen as above.
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