Jul 27, 2008

Performance of the pathology of chronic cervicitis

Cervical erosion is a chronic inflammatory disease cervicitis up to see the process of the local features. Cervical surface of red lesions, squamous cell loss, replaced by columnar epithelium, the skin on the vessel revealed the results. And the erosion of the surrounding normal squamous cell there were clear limits. Erosion due to non-real, also known as "pseudo-erosion" ( "pseudoerosion").

In some chronic cervicitis can have all kinds of different manifestations:

1, cervical erosion (cervical erosion)

Cervical erosion is a chronic inflammatory disease cervicitis up to see the process of the local features. Cervical surface of red lesions, squamous cell loss, replaced by columnar epithelium, the skin on the vessel revealed the results. And the erosion of the surrounding normal squamous cell there were clear limits. Erosion due to non-real, also known as "pseudo-erosion" ( "pseudoerosion"). According to the degree of inflammation and columnar epithelial growth rate.

Cervical erosion can be expressed as three types.

(A) simple: in the early inflammation, erosion of the columnar epithelium covered by the single-layer, the surface flat, smooth appearance.

(B) particle type: cervical epithelium because of the excessive proliferation and the proliferation of quality, erosion of rugged, and a granular.

(C) papillary type: gland epithelial and stromal hyperplasia significantly, significantly more rugged surface, forming

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Papillary processes.

According to Chang erosion of its area divided into mild, moderate and severe. Where cervical erosion of the total area of less than 1 / 3 of those for light (Ⅰ °), accounting for 1 / 3 to 1 / 2 to moderate (Ⅱ °), more than 1 / 2 to total area of severe (Ⅲ °) .

In particular, the cervix is the erosion of the healing process. Inflammatory diseases weakened slightly in the circumstances, squamous cell adjacent to the erosion of coverage on the skin of the columnar growth, gradually epithelium passes, the last fully recovered and squamous cell coverage. Such direct replacement by squamous cell although the situation there, but the alternative is even more indirect Most of that is in columnar regular presence on the skin of his small round cell, said basal cell (basal cell) or reserve cells (recell ), The erosion of the healing process of proliferation of these cells, into the final of the squamous cell. Erosion of healing Chang Cheng-block distribution: a result of this new and squamous cell growth in the inflammatory organizations on the basis of, the cell surface shedding and thinning vulnerable, and that is slightly stimulated by the resumption of erosion. Therefore, the expansion of healing and inflammation in turn, treatment is not complete, it is extremely difficult to recover.

The healing process, not only in the surface erosion, the implicit Au adenoid glands and the proliferation of space covered by the columnar epithelium-the same can be replaced by epithelial layer. This epithelium and the rehabilitation of the epidermal layer of (epidermization), commonly referred to as "squamous metaplasia" (squamous metaplasia). Metaplasia level are very different, and sometimes epithelium were replaced, sometimes only one side of the gland or glands by the opening of alternative, some form of the adenoid substantive cells in the cervix among clumps of quality. Man Xingzi cervicitis due to the high incidence rate, which in cervical biopsy, squamous metaplasia found that the rate can be as high as 70 to 80 percent. Squamous metaplasia healing process is rotten to the core of a change, there is no tendency to cancer, precancerous lesions is not, and should not be changed between (anaplasia) or atypical hyperplasia (atypical hyperplasia) confusion.

In addition, the formation of cervical erosion there may be two reasons:

1 congenital erosion: in the latter part of embryonic development, vaginal and cervical part of the vagina are covered by the TCC, to six months, the epithelium to the neck of the extension, until full-term, the cervical mucous membrane of the columnar Epithelial growth outward, beyond the cervix, mouth, about 1 / 3 newborn baby to maintain such status, its look and adult inflammatory similar to cervical erosion, there was a "congenital cervical erosion," said, but generally only lasted There a few days, from mother to the level of estrogen after landing, that is, naturally dissipated; ② due to cervical endometrial columnar epithelial hyperplasia, beyond the cervix, mouth caused by cervical erosion, with the appearance of inflammatory cervical erosion, only occurred in ovarian function The growing period vigorous age, but not occur in puberty or after menopause, and occurs in pregnancy, postpartum and often have the tendency to self-dissipated. Although the increase in flu patients Leucorrhea However, in order to clean mucus, pathological examination in the column on the skin no infiltration of inflammatory cells, or only see a small number of lymphocytes, and above the papillary and adenoid erosion characterized as the organization. All these phenomena are sufficient to note the formation of such erosion, may be the sex hormone imbalance, and has nothing to do with the inflammation, but the erosion on the basis of possible secondary inflammation, but this is only a consequence rather than the causes of erosion. Erosion may be because of the role of estrogen, but some animal experiments found that one injection of testosterone after a similar erosion of the gland changes. So that androgen can change as cervical intraepithelial mucous glands and tend to be formed, the role of progesterone in this area similar to androgen, estrogen's role is to become a highly keratinized epithelial hyperplasia of the rehabilitation of the flat epithelial

To sum up, the cause of cervical erosion in addition to the vast majority of inflammation, may also caused by endocrine disorders. On the differential in the period and should pay attention to whether the incentives associated with inflammation and signs, also for reference pathological examination, treatment is also slightly different.

In Man Xingzi cervicitis, cervical gland and surrounding tissue are hyperplasia. When Xianguan been squeezed by the surrounding tissue, I blocked gland, the gland secretions can not drain and retention in, to the gland cavity expansion, ranging from the size of a capsule-shaped mass, known as the "cervical gland retention cyst ", Also known as Naboth. It contains the clear mucous often transparent, but the merger may be due to infection with turbidity Nongxing. Cyst generally small and scattered, can be prominent on the surface of the cervix. Only a small small grain of rice, maize grain up to the big, a Qing Baise, may be accompanied by erosion, but also common in the smooth surface of the cervix. As the long-term chronic inflammatory stimulation, cervical organizations recurring congestion, edema, infiltration of inflammatory cells and connective tissue proliferation, causing the cervix mast (cervical-hypertrophy), serious than normal cervix can increase more than doubled. Inflammation recovery, congestion, reduce edema, or dissipated, and as fibrosis, despite all the lining of cervical squamous cell, smooth surface, but still maintain the size of their mast; cervical cyst also still maintain its prominent cystic appearance.

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